The story Chiusa Sclafani, as the story of all the feuds is largely tied to that of the noble families who over the centuries acquired ownership through marriage or by royal investiture.

Early Settlement
It is unclear when the town of Chiusa Sclafani was first established, in 1887 a necropolis was discovered. The archaeology suggests a settlement of the Byzantine epoch. When the Greeks settled the coastal regions the Sicani retreated into the mountains, it is possible that a Sicani settlement existed that was further developed by the Byzantine. The name of this settlement is unknown and lost to us.
What we know of the region, is from the Aragon period.  Matteo Sclafani built a castle and that this then allowed the township of Chiusa to be established.

What do we know about the Sclafani Family?
The surname "Sclafani" is derived from the Greek "Aesculapii fanum," meaning "Sacred to the god Aesculapius," the Greek god of medicine. The Greek version of the surname Sclafani, "Sclavounos", can be located in the "Dictionnaire Historique et Généalogique des Grandes Familles de Grèce", a book which contains information about Greek nobility. The exact surname "Sclafani" can be found in the "Dizionario Storico Blasonico", an armorial of noble Italian family lineages. It states that the family originated in or around the region of Lombardy, which borders present day Switzerland, and ancient Gaul (mostly modern France). There had been numerous Lombard, or Longobard mercenaries and petty nobles in southern Italy since at least the early 11th century, and Roger d'Hauteville brought many with his Norman contingent on his invasion of Sicily and subsequent conquest of the island from the Muslims.

The Sclafani family was moved to Palermo, under direction of Giovanni Sclifano, ally of the Norman ruler William I of Sicily. This may have been part of the on-going royal policy of centralisation of power in the hands of the monarch throughout southern Italy and Sicily begun by William's father, Roger II.
In Sicily, Giovanni Sclifano was given the Castle Megerio by the king to show his gratitude for having Giovanni's support in the conspiracy of Matthew Bonello.
A son of Giovanni, Goffredo Sclifano, founded a monastery in Lentini around the year 1185.
Matteo Sclafani, became count of Adernò in 1303, who became Count and Lord of Chiusa Sclafani in 1330. Aside from being involved with the Knights Templar, he built many palaces and cathedrals throughout Italy including a magnificent royal palace in Palermo, the monastery of Santa Chiara, the church of Sant'Agostino, and of S. Niccolò dell'Albergaria. He died in the year 1354.

The Greek association with the name lends to some speculation, I am more inclined to think that the Sclafani where Longobard arriving with the first Norman’s (Roger I). On the other hand they could have existed in Sicily during the Greek and or Byzantine period, Later with the political manoeuvring in the 11th century aligned with the Longobard. Remembering that Magnia Grecia included a great part of Italy, so speculation is all that is left, factual evidence is difficult to obtain.  I find conflicting narration’s on the name Sclafani and that of Matteo. In one source it claims that his parents were Francesca e Berardo Actarino. I know that during this period names changed to reflect the holdings of the family. This makes it difficult without access to other historical documents to find the true names of the people involved.